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史宣玲

完美体育·(中国)官方网站副研究员

E-mail: shixuanlingsk@tsinghua.edu.cn

Tel: +86-10- 62797532

  • 个人简历

  • 科研领域及主要成果

  • 代表性论著

  • 其他信息

史宣玲研究员1993年本科毕业于华西医科大学,2000年获得协和完美体育·(中国)官方网站病原生物学博士。2001-2004年在北京大学、2005-2008年在爱因斯坦完美体育·(中国)官方网站从事博士后研究工作,2008年至今在完美体育·(中国)官方网站工作。主要从事艾滋病与新发突发病毒性传染病抗体药物与疫苗研究。

艾滋病与新发突发病毒性传染病抗体药物与疫苗研究

史宣玲研究员的科研重点是艾滋病病毒与免疫系统相互作用关系、抗艾滋病病毒药物和疫苗的研发、以及抗新发突发传染病的单克隆抗体和疫苗的研发等。

1.Li Mingxi, Guo Jingao, Lu Shuaiyao, Zhou Runhong, Shi Hongyang, Shi Xuanling, Cheng Lin, Liang Qingtai, Liu Hongqi, Wang Pui, Wang Nan, Wang Yifeng, Fu Lili, Xing Man, Wang Ruoke, Ju Bin, Liu Li, Lau Siu-Ying, Jia Wenxu, Tong Xin, Yuan Lin, Guo Yong, Qi Hai, Zhang Qi, Huang Zhen, Chen Honglin, Zhang Zheng, Chen Zhiwei, Peng Xiaozhong, Zhou Dongming, Zhang Linqi. (2021). Single-dose immunization with a chimpanzee adenovirus-based vaccine induces sustained and protective immunity against SARS-CoV-2 infection. Frontiers in Immunology, 12, 1–14. https://doi.org/10.3389/fimmu.2021.697074

2.Ju Bin, Zhang Qi, Ge Jiwan, Wang Ruoke, Sun Jing, Ge Xiangyang, Yu Jiazhen, Shan Sisi, Zhou Bing, Song Shuo, Tang Xian, Yu Jinfang, Lan Jun, Yuan Jing, Wang Haiyan, Zhao Juanjuan, Zhang Shuye, Wang Youchun, Shi Xuanling, Liu Lei, Zhao Jincun, Wang Xinquan, Zhang Zheng, Zhang Linqi. (2020). Human neutralizing antibodies elicited by SARS-CoV-2 infection. Nature, 584(7819), 115–119. https://doi.org/10.1038/s41586-020-2380-z

3.Zhou Panpan, Wang Han, Fang Mengqi, Li Yangyang, Wang Hua, Shi Shasha, Li Zihao, Wu Jiapeng, Han Xiaoxu, Shi Xuanling, Shang Hong, Zhou Tongqing, Zhang Linqi. (2019). Broadly resistant HIV-1 against CD4-binding site neutralizing antibodies. PLoS Pathogens, 15(6), 1–24. .

4.Jiang Liwei, Wang Nianshuang, Zuo Teng, Shi Xuanling, Poon Kwok Man Vincent, Wu Yongkang, Gao Fei, Li Danyang, Wang Ruoke, Guo Jianying, Fu Lili, Yuen Kwok Yung, Zheng Bo Jian, Wang Xinquan, Zhang Linqi. (2014). Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein. Science Translational Medicine, 6(234). https://doi.org/10.1126/scitranslmed.3008140

5.Wang Nianshuang, Shi Xuanling, Jiang Liwei, Zhang Senyan, Wang Dongli, Tong Pei, Guo Dongxing, Fu Lili, Cui Ye, Liu Xi, Arledge Kelly C., Chen Ying Hua, Zhang Linqi, Wang Xinquan. (2013). Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4. Cell Research, 23(8), 986–993. https://doi.org/10.1038/cr.2013.92

开设课程

医学微生物学