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Nov 29, 2017
Yefeng TANG publishes "Enantioselective and Collective Total Syntheses of Xanthanolides" in Angew. Chem. Int. Ed.

An enantioselective synthesis of (+)-8-epi-xanthatin hinging on a chiral phosphoric acid catalyzed tandem allylboration/lactonization reaction is reported. With (+)-8-epi-xanthatin as the precursor, t...
Nov 27, 2017
Bailong XIAO publishes"A protein interaction mechanism for suppressing the mechanosensitive Piezo channels" in Nature Communications

Piezo proteins are bona fide mammalian mechanotransduction channels for various cell types including endothelial cells. The mouse Piezo1 of 2547 residues forms a three-bladed, propeller-like homo-trim...
Nov 16, 2017
Dr. Chen Dong Selected for the Prestigious List of Highly Cited Researchers 2017...

Thomson Reuters announced the list of Highly Cited Researchers 2017, and Dr. Chen Dong is selected for the only scientist in the discipline of immunology in Mainland China. Highly Cited Researche...
Nov 16, 2017
Babak Javid Receives Wellcome Trust Investigator Award...

Babak Javid, from School of Medicine, Tsinghua University was recently appointed an Investigator of the Wellcome Trust with a project titled “Molecular characterisation of antibiotic tolerance in&nbs...
Nov 12, 2017
New Drug Research and Development Series: the academic seminar on computer-aided drug design was successfully held

November 11th to 12th, 2017 -- the "New Drug Research and Development Series: the academic seminar on computer-aided drug design”, hosted by the SPS of Tsinghua University, was successfully held in T...
Oct 23, 2017
President Yong Qiu visited SPS of Tsinghua University with the encouragement on the exploration and development of new models and mechanisms

October 23 --- Yong Qiu, President of Tsinghua University, visited the SPS to conduct research on discipline planning, student training and platform construction, encouraging the School to further det...
Sep 19, 2017
Ligong CHEN publishes"A Network Integration Approach for Drug-Target Interaction Prediction and Computational Drug Repositioning from Heterogeneous Information

The emergence of large-scale genomic, chemical and pharmacological data provides new opportunities for drug discovery and repositioning. In this work, we develop a computational pipeline, called DTINe...
Sep 07, 2017
The 2017 Chinese Medicinal Chemistry Symposium Held in Beijing to Advance Global New Drug Research and Development

Beijing, August 27th to 30th, the 2017 Chinese Medicinal Chemistry Symposium (CMCS), organized by Chinese Pharmaceutical Association and co-organized by School of Pharmaceutical Sciences of ...
Sep 05, 2017
Ligong CHEN publishes"Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity" in Archives of Toxicology

Zoledronate is a bisphosphonate that is widely used in the treatment of metabolic bone diseases. However, zoledronate induces significant nephrotoxicity associated with acute tubular necrosis and rena...
Aug 24, 2017
Prof. Brian Kobilka’s group revealed the mechanism of intracellular allosteric ...

On August 17th, 2017, Prof. Brian Kobilka’s research group in school of Medicine, Tsinghua University published a paper in Nature, entitled “Mechanism of intracellular allosteric β2AR antagonist re...

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Yefeng TANG publishes "Enantioselective and Collective Total Syntheses of Xanthanolides" in Angew. Chem. Int. Ed.

An enantioselective synthesis of (+)-8-epi-xanthatin hinging on a chiral phosphoric acid catalyzed tandem allylboration/lactonization reaction is reported. With (+)-8-epi-xanthatin as the precursor, t...

Bailong XIAO publishes"A protein interaction mechanism for suppressing the mechanosensitive Piezo channels" in Nature Communications

Piezo proteins are bona fide mammalian mechanotransduction channels for various cell types including endothelial cells. The mouse Piezo1 of 2547 residues forms a three-bladed, propeller-like homo-trim...

Dr. Chen Dong Selected for the Prestigious List of Highly Cited Researchers 2017...

Thomson Reuters announced the list of Highly Cited Researchers 2017, and Dr. Chen Dong is selected for the only scientist in the discipline of immunology in Mainland China. Highly Cited Researche...

Babak Javid Receives Wellcome Trust Investigator Award...

Babak Javid, from School of Medicine, Tsinghua University was recently appointed an Investigator of the Wellcome Trust with a project titled “Molecular characterisation of antibiotic tolerance in&nbs...

New Drug Research and Development Series: the academic seminar on computer-aided drug design was successfully held

November 11th to 12th, 2017 -- the "New Drug Research and Development Series: the academic seminar on computer-aided drug design”, hosted by the SPS of Tsinghua University, was successfully held in T...

President Yong Qiu visited SPS of Tsinghua University with the encouragement on the exploration and development of new models and mechanisms

October 23 --- Yong Qiu, President of Tsinghua University, visited the SPS to conduct research on discipline planning, student training and platform construction, encouraging the School to further det...

Ligong CHEN publishes"A Network Integration Approach for Drug-Target Interaction Prediction and Computational Drug Repositioning from Heterogeneous Information

The emergence of large-scale genomic, chemical and pharmacological data provides new opportunities for drug discovery and repositioning. In this work, we develop a computational pipeline, called DTINe...

The 2017 Chinese Medicinal Chemistry Symposium Held in Beijing to Advance Global New Drug Research and Development

Beijing, August 27th to 30th, the 2017 Chinese Medicinal Chemistry Symposium (CMCS), organized by Chinese Pharmaceutical Association and co-organized by School of Pharmaceutical Sciences of ...

Ligong CHEN publishes"Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity" in Archives of Toxicology

Zoledronate is a bisphosphonate that is widely used in the treatment of metabolic bone diseases. However, zoledronate induces significant nephrotoxicity associated with acute tubular necrosis and rena...

Prof. Brian Kobilka’s group revealed the mechanism of intracellular allosteric ...

On August 17th, 2017, Prof. Brian Kobilka’s research group in school of Medicine, Tsinghua University published a paper in Nature, entitled “Mechanism of intracellular allosteric β2AR antagonist re...

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